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177Lu-DOTA therapy – 100 mCi
₹100000
177Lutetium-DOTA therapy is planned to treat neuroendocrine origin tumours spread in the body from different primary sites, including the gastrointestinal tract, lung, pancreas, and thymus. This therapy is also called peptide receptor radionuclide therapy (PRRT). Generally, this is given in 3-5 cycles with a 6-12 weeks gap.
Test information: Fasting: 2 hours
Reporting: Not applicable
- Some medications, such as Somatostatin analogues, may interfere with this treatment. The long-acting medicines may need to withdraw for 4-6 weeks, and short-acting may need to stop for 24 hours. Kindly ensure this in consultation with your doctor.
- In pre-work up, blood tests such as complete blood count (CBC), liver and kidney function tests (LFT, KFT), and serum electrolytes are carried out before each treatment cycle and at follow-up visits.
- 68Ga-DOTANOC PET/CT scan is done before the treatment and after the completion of each two cycles of 177Lu-DOTA therapy, and after the entire treatment.
- CBC, LFT, and KFT tests are performed every 8–12 weeks for the first 12 months and twice a year if clinically indicated.
- During the first 2 days after PRRT, the high activity level is excreted. Patients are advised to avoid contamination of toilets and flush the toilet twice. Patients should wash their hands after urination.
- Patients should avoid soiling underclothing or areas around toilet bowls for 1 week following PRRT. Considerably contaminated clothing should be washed separately.
- Incontinent patients should be catheterized before PRRT, and the catheter should be kept for 2 days after that. Urine bags should be emptied frequently.
- Gloves and protective clothing should be worn by the person caring for catheterized patients (or providing any care involving close contact).
- Women of childbearing age should avoid pregnancy for at least 6 months. Male patients should consider sperm banking before therapy.
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